Integrated Research and
Treatment Center Transplantation
The MHH (Hannover Medical School) is one of the the largest comprehensive transplant centers in Europe. In 2008 the MHH has founded the Integrated Research and Treatment Center Transplantation (IFB-Tx) to integrate and focus transplantation medicine and research.
The IFB-Tx is supported by a generous grant of the Federal Ministry of Research (BMBF) of 25 M EURO from 2008 until 2013. The support is part of a national competition for excellence in clinical research.
The overall aim of the IFB-Tx is to integrate all basic and clinical departments involved in transplantation into an effective unit to develop new diagnostic and therapeutic strategies to rectify the current limitations of transplant medicine.
Solid organ and cell-based (bone marrow cells, stem cells, islet cells and others) transplantation has made considerable progress in the past years; however, graft survival remains limited and side effects of immunosuppressive medication are considerable. Moreover, mortality of transplanted patients is still unacceptably high. Haematopoietic stem cell transplantation, disease relapse and graft-versus-host disease (GvHD) result in considerable morbidity and mortality.
The large numbers of solid organ and cell transplants performed at the MHH allows the IFB-Tx to perform large-scale clinical and basic studies addressing important questions in the area of transplant medicine. We aim to substantially influence national and international standards in this regard and to facilitate appropriate diagnostic and therapeutic changes.
Our goals are
We are well underway to reach these goals.